Primary Mucosal Melanoma: Uncommonly Described Entity
نویسنده
چکیده
Malignant melanoma arises by malignant transformation of the normal melanocytes. Distribution of malignant melanoma includes cutaneous (91.2%), ocular (5.3%), mucosal (1.3%), and unknown primary site (2.2%) [1]. Because of rarity and clinical challenges arising from different anatomic location, our understanding for the optimal management of mucosal melanoma remains limited. Malignant melanoma can arise from the mucosal epithelium of respiratory, alimentary, and genitourinary tracts, all of which contain melanocytes. The most common sites for primary mucosal melanoma include head and neck followed by anorectal, and vulvovaginal regions (55, 24, and 18%, respectively). Rarer sites are urinary tract, gallbladder, and small intestine.
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